Warfarin Institute of America

DEDICATED TO YOUR HEALTH SINCE 2000

DEVIL'S CLAW INTERACTIONS WITH WARFARIN (Coumadin, Jantoven)

Botanical name: Harpagophytum procumbens

  Devil’s claw is used as an analgesic and anti-arthritic. There is one case report in the literature of a possible interaction with warfarin (Coumadin, Jantoven), however, the mechanism by which this occurred is unknown.

Case report:

  Increased bruising was reported to the Medical Toxicology Unit, London, when a patient concurrently took devil’s claw and warfarin (Coumadin, Jantoven). No other details about this case are available. Based upon this evidence, this interaction is unlikely to be clinically significant.

References:

Shaw D, Leon C, Kolev S, Murray V. Traditional remedies and food supplements: a five year toxicological study (1991-1995). Drug Safety 1997; 17:342-56.

© 2001 Patricia Chuong Used by permission.

An editorial about the lack of concern for manufacturers of these products and their interactions with other medications.

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Last modified May 11, 2006