Warfarin Institute of America

DEDICATED TO YOUR HEALTH SINCE 2000

DONG QUAI INTERACTIONS WITH WARFARIN

  There has been only one case of this interaction reported in the medical literature.  This was discovered by an acquaintance of mine, Dr. Robert Lee Page II.  

  The patient had been taking warfarin for a couple of years with the INR and the dose remaining stable.  Her herbalist recommended dong quai for the treatment of peri-menopausal complaints.  This was the only change she had made which could account for her INR suddenly jumping from the 2 to 3 range to 4.9.  When she stopped the dong quai, her INR gradually returned to the 2 to 3 range on the same warfarin dose.

  Due to this report, it would be advisable to avoid dong quai if you are taking warfarin.

Reference: Page RL et al. Potentiation of Warfarin by Dong Quai.  Pharmacotherapy. 1999;19:870-6.

The assistance of Patricia Chuong in researching this is acknowledged.

An editorial about the lack of concern for manufacturers of these products and their interactions with other medications.

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Last modified August 17, 2006