Warfarin Institute of America
DEDICATED TO YOUR HEALTH SINCE 2000
What role do anticoagulants play
in the treatment of Lemierre syndrome? - Sarah
Lemierre syndrome is cause by a bacterial
infection in the mouth and throat which usually cause a painful, swollen neck.1
If not treated promptly, this rare infection can be life-theatening.1
Although this syndrome causes a clot to form in a large vein in the neck, the
use of warfarin is controversial. 2 There are no controlled studies that
have examined the effects of warfarin on Lemierre syndrome, however, it
may be beneficial in some cases. Warfarin may decrease the time to clear
the infection and clot.3
REFERENCES:
1. Fleskens AJ, Scheltinga MR, van Eerten PV et al. [Sore throat and a swollen
neck: Lemierre's syndrome until proven otherwise]. Ned Tijdschr Geneeske.
2006 Nov 11; 150(45): 2461-6.
2. Golpe R, Marin B, Alonso M. Lemierre's syndrome (necrobacillosis).
Postgrad Med J. 1999 Mar; 75(881): 141-4.
3. Ramirez S, Hild TG, Rudolph CN, et al. Increased Diagnosis of Lemierre
Syndrome and Other Fusobacterium necrophorum Infections at a Children's
Hospital. Pediatrics. 2003 Nov; 112(5): 384.
©2007 Bridget Slevin Used by permission.
Editor's Note: This
syndrome has been rarely seen since the advent of treating "sore throats" with
antibiotics in the 1940s and 1950s. With the rise of antibiotic-resistant
bacteria the pressure to use less antibiotics may result in this syndrome might
be seen more often. Many doctors are completely unaware of this condition.
This is because it has been so rarely seen for so long that it is hardly taught
in medical schools.
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Last updated June 18, 2007
