Warfarin Institute of America

Dedicated to Your Health

IBUPROFEN INTERACTION WITH WARFARIN

Brand Names: Motrin, Advil, Motrin IB, Genpril, Haltran, Maximum Strength Midol, Menadol, Nuprin, Pedia-Care Fever,  Vicoprofen, and many others.

  Ibuprofen can cause gastrointestinal bleeding.  If this should occur and you are taking warfarin, a minor bleed could turn out to be a major bleed.  

  There are three factors that contribute to this: 

  • Physicians are careless in their prescribing of ibuprofen. 
  • Patients are careless when they purchase ibuprofen as a non-prescription item. 
  • There is no warning that this is about to happen because the INR is not raised.

  If at all possible, ibuprofen use should be avoided when you are taking warfarin.

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Last updated November 13, 2004