Warfarin Institute of America

Dedicated To Your Health

THE INTERACTION BETWEEN ROSUVASTATIN AND WARFARIN

Brand Name: Crestor

  The AstraZeneca information for Crestor says that this might happen.  However, this is a new drug and there are no actual case reports in the medical literature, so this is a first.

10-31 a man on warfarin started Crestor. He is not my patient but a friend who self tests, so I don't know the INR that day. 

11-2 INR was 2.5, kept the same warfarin dose. 

11-19 INR was 4.6. He is reducing the warfarin dose. 

  Looks like it will be a good idea to check the INR about 1 week after someone on warfarin starts rosuvastatin.  However, it has been more than one year since I received this report and there are no more listed in the medical literature, so I think that this must be a fairly rare occurrence.

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Last updated November 21, 2004